A customer shops at a GNC store in New York in 2013.

Many consumers are devoted to vitamin supplements, a multibillion-dollar industry.

Tired? Take an iron supplement. Sad? Classic vitamin D deficiency.

But a recent paper related to cardiovascular health, published July 9 in Annals of Internal Medicine, put this loyalty to the test. It suggested that vitamin supplements had little impact on heart conditions, including heart disease, and lifespan as a whole.

According to Dr. Erin D. Michos, associate professor of medicine in cardiology at Johns Hopkins School of Medicine and one of the paper’s co-authors, the paper was catalyzed in part by the growing popularity of the supplement industry.

“An estimated 1 out of 2 Americans are taking some kind of supplement or vitamin,” Michos said. “For the vast majority of vitamins, we did not find any benefit, either in reduction in death or cardiovascular health.”

While vitamin devotees might feel betrayed, medical professionals are less surprised. The paper reviewed collective evidence from separate randomized clinical trials to analyze the benefit of dietary intervention and supplementation in cardiovascular conditions.

Dr. Jeffrey Linder, chief of internal medicine and geriatrics at Northwestern Medicine, wasn’t surprised by the results, which corroborated and combined years of research while putting a spotlight on cardiovascular health.

“This new study confirms what we’ve been thinking all along: that there are very few, if any, supplements or vitamins that people should take as long as you’re eating a healthy diet,” Linder said. “Every time scientists have compared taking a supplement of something versus getting it through food, getting it through food wins every time.” Food, Linder said, contains both minerals and vitamins that the body is “built and designed to absorb.”

Dr. Mark Rabbat, a Loyola Medicine cardiologist, said that he would only prescribe a supplement to patients with established vitamin deficiencies who may derive benefits, but this is not the majority. Still, patients crave what Rabbat called “that magic pill,” and their desire for an easy fix makes a target of the supplement industry.

Vitamins are considered food supplements and are not regulated by the Food and Drug Administration, and Rabbat said they’re often vague in labeling as a result — claiming, for instance, to be “good for the heart” without explaining why. Dr. Rami Doukky, chair of cardiology at Cook County Health, Chicago, said that the industry promotes itself as though its claims were substantiated.

“You cannot watch television and avoid these advertisements for all kinds of vitamins,” Doukky said. “They convince patients of a certain age group that they need to take vitamins.”

Though the paper demonstrated some evidence that omega-3 fatty acids could help prevent heart attacks, it also demonstrated that taking a certain combination of supplements — calcium plus vitamin D — was shown to increase risk for stroke. While some supplements are considered benign, if ineffective (with the exception of their usage to treat deficiencies), this clearly isn’t always the case.

“It can be hard to convince people if they feel pretty good and feel like what they’ve been doing is healthy,” Linder said. “I get their resistance, and the idea that this new study is going to make everybody drop their supplements is unrealistic too.”

There are, in fact, dietary regulations that Doukky said are known to aid heart health: eating fresh fruits, vegetables and whole grains, exercising regularly and avoiding smoking. He said most people should save their money and not buy supplements.

“In my mind, if it’s not harmful, it’s a waste of money,” Doukky said.

© 2019 The Associated Press. All rights reserved. This material may not be published, broadcast, rewritten or redistributed.

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