The Iowa Department of Public Health reported two new cases of the Zika virus on Friday.
The two women had recently traveled to countries where the virus is prevalent. They raise Iowa's total Zika cases to three.
Nebraska reported that the Zika virus was found in two women early this month. Nebraska has reported no additional cases.
The Iowa health agency said the general public isn't at risk of contracting the virus because the particular mosquitoes that transmit the disease aren't in the state at this time. The mosquito that is the primary carrier, Aedes aegypti, lives in tropical and sub-tropical places.
Those traveling to countries where there is ongoing Zika transmission should protect themselves from mosquito bites, the Iowa agency said.
Nations and territories where Zika is prevalent include many in South America, Central America and the Caribbean.
Most people who contract the virus don't become ill, or become only mildly sick. But pregnant women who contract the virus may have babies with microcephaly, a condition that may include brain damage.