Metropolitan Utilities District crews were repairing an 18-inch water main at 28th and Farnam Streets on Wednesday.
The break occurred Tuesday night, MUD said.
Four or five commercial customers in the area of 24th to 29th Streets were affected by the break.
MUD said water was to be shut off from approximately 5 p.m. to 7 p.m. Wednesday to allow the crews to install a new valve.
One westbound lane has been closed on Farnam Street, from 27th Street to 29th Street, MUD said.